DHX40

Across TCGA cell cohorts, DHX40 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,252 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DHX40-associated GO terms across cancer lineages are Transport along microtubule, Protein localization to cilium, and Negative regulation of beige fat cell differentiation. Each is linked with DHX40 in more than 15 cancer types. Because this analysis shows association rather than direction, both DHX40-to-partner and partner-to-DHX40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transport along microtubule grouped by DHX40-low versus DHX40-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX40→partner) and Y-score (partner→DHX40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Transport along microtubule →	+0.080	+0.910	<.001	<.001	3	16
LIVER	Protein localization to cilium →	+0.079	+1.171	.001	.003	3	15
LIVER	Negative regulation of beige fat cell differentiation →	+0.191	+1.096	<.001	<.001	3	15
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.082	+0.950	<.001	<.001	3	13
LUNG_SCLC	Microtubule-based transport →	+0.073	+0.966	<.001	<.001	3	13
LUNG_SCLC	Regulation of organelle assembly →	+0.051	+0.826	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,252 associations by consensus.

Transport along microtubule by DHX40 expression — LUNG_SCLC

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