DHX38

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DHX38 protein abundance is significantly associated with the RNA expression of many other genes, with 17,217 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DHX38-associated genes across cancer lineages are NAE1, VPS4A, and DDX19B. Each is linked with DHX38 in more than 9 cancer types. Because this analysis shows association rather than direction, both DHX38-to-partner and partner-to-DHX38 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHX38 versus NAE1 in LSCC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX38→partner) and Y-score (partner→DHX38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCNAE1 →+0.578+0.209<.001<.001310
BRCAVPS4A →+0.439+0.206<.001<.00139
OVDDX19B →+0.647+0.354<.001<.00139
OVAP1G1 →+0.794+0.283<.001<.00139
GBMTMEM170A →+0.603+0.217<.001<.00139
OVSPG7 →+0.626+0.244<.001.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,217 associations by consensus.

DHX38 vs NAE1 — LSCC

Per-sample scatter of DHX38 vs NAE1 in LSCC (Pearson r = 0.54).

Explore this scatter interactively →

Exploration