DHX38

Across TCGA cell cohorts, DHX38 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,486 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DHX38-associated GO terms across cancer lineages are Viral transcription, RNA localization, and Promoter clearance during DNA-templated transcription. Each is linked with DHX38 in more than 16 cancer types. Because this analysis shows association rather than direction, both DHX38-to-partner and partner-to-DHX38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral transcription grouped by DHX38-low versus DHX38-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX38→partner) and Y-score (partner→DHX38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Viral transcription →	+0.130	+0.896	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	RNA localization →	+0.117	+1.117	<.001	<.001	3	17
KIDNEY	Promoter clearance during DNA-templated transcription →	+0.128	+0.866	.005	.002	3	16
KIDNEY	RNA polymerase II promoter clearance →	+0.128	+0.866	.005	.002	3	16
BONE	Negative regulation of t-circle formation →	+0.132	+0.687	<.001	.004	3	16
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mRNA splicing, via spliceosome →	+0.154	+1.001	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,486 associations by consensus.

Viral transcription by DHX38 expression — BONE

Explore this box plot interactively →