DHX37

Across TCGA pan-cancer cohorts, DHX37 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of DHX37’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where DHX37 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DHX37 is over-expressed in tumor.

COAD, HNSC, and KIRC are the cancer types where DHX37 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DHX37 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+1.150	<.001	12	view →
HNSC	Male	All	+0.902	<.001	12	view →
KIRC	Male	IV	+0.754	<.001	12	view →
KIRP	All	II,III,IV	+1.233	<.001	11	view →
BLCA	Female	III,IV	+1.035	<.001	11	view →
STAD	Male	II,III,IV	+1.475	<.001	9	view →
LIHC	Male	II,III,IV	+1.230	<.001	9	view →
LUAD	All	III,IV	+0.915	<.001	9	view →
LUSC	Male	III,IV	+1.587	<.001	8	view →
UCEC	All	All	+0.541	.007	6	view →
BRCA	All	All	+0.360	<.001	6	view →
CHOL	Male	All	+2.318	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

DHX37–COAD

Open the COAD breakdown →