DHX36

Across TCGA cell cohorts, DHX36 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,923 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DHX36-associated GO terms across cancer lineages are Positive regulation of mRNA processing, Response to arsenite ion, and Cellular response to arsenite ion. Each is linked with DHX36 in more than 18 cancer types. Because this analysis shows association rather than direction, both DHX36-to-partner and partner-to-DHX36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA processing grouped by DHX36-low versus DHX36-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX36→partner) and Y-score (partner→DHX36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of mRNA processing →	+0.125	+0.954	<.001	<.001	3	19
LIVER	Response to arsenite ion →	+0.132	+0.849	<.001	<.001	3	18
LIVER	Cellular response to arsenite ion →	+0.132	+0.849	<.001	<.001	3	18
OESOPHAGUS	Positive regulation of cytoplasmic translation →	+0.113	+0.582	<.001	<.001	3	18
PANCREAS	Double-strand break repair via homologous recombination →	+0.081	+0.594	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.064	+0.674	.002	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,923 associations by consensus.

Positive regulation of mRNA processing by DHX36 expression — KIDNEY

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