DHX35

Across TCGA patient cohorts, DHX35 protein abundance is significantly associated with the RNA expression of many other genes, with 11,196 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DHX35-associated genes across cancer lineages are GPATCH1, CEP89, and FAAP24. Each is linked with DHX35 in more than 6 cancer types. Because this analysis shows association rather than direction, both DHX35-to-partner and partner-to-DHX35 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHX35 versus GPATCH1 in OV, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX35→partner) and Y-score (partner→DHX35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GPATCH1 →	+0.552	+0.288	<.001	<.001	3	7
HNSC	CEP89 →	+0.791	+0.304	<.001	<.001	3	6
OV	FAAP24 →	+0.599	+0.310	.002	<.001	3	6
HNSC	LSM14A →	+0.821	+0.248	.001	<.001	3	6
HNSC	UBA2 →	+0.909	+0.322	<.001	<.001	3	6
HNSC	CEBPG →	+0.917	+0.289	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,196 associations by consensus.

DHX35 vs GPATCH1 — OV

Explore this scatter interactively →