DHX35

Across TCGA cell cohorts, DHX35 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,441 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DHX35-associated GO terms across cancer lineages are RNA export from nucleus, Promoter clearance during DNA-templated transcription, and RNA polymerase II promoter clearance. Each is linked with DHX35 in more than 17 cancer types. Because this analysis shows association rather than direction, both DHX35-to-partner and partner-to-DHX35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA export from nucleus grouped by DHX35-low versus DHX35-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX35→partner) and Y-score (partner→DHX35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	RNA export from nucleus →	+0.097	+0.683	<.001	<.001	3	18
OVARY	Promoter clearance during DNA-templated transcription →	+0.114	+0.640	<.001	<.001	3	17
OVARY	RNA polymerase II promoter clearance →	+0.114	+0.640	<.001	<.001	3	17
BONE	Nucleic acid transport →	+0.120	+0.929	.003	<.001	3	17
BONE	RNA transport →	+0.120	+0.929	.003	<.001	3	17
BONE	Regulation of double-strand break repair via homologous recombination →	+0.108	+0.867	.005	.002	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,441 associations by consensus.

RNA export from nucleus by DHX35 expression — STOMACH

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