DHX33

Across TCGA cell cohorts, DHX33 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,892 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DHX33-associated GO terms across cancer lineages are XMP metabolic process, XMP biosynthetic process, and 'de novo' XMP biosynthetic process. Each is linked with DHX33 in more than 18 cancer types. Because this analysis shows association rather than direction, both DHX33-to-partner and partner-to-DHX33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XMP metabolic process grouped by DHX33-low versus DHX33-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX33→partner) and Y-score (partner→DHX33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	XMP metabolic process →	+0.206	+1.279	<.001	<.001	3	19
BONE	XMP biosynthetic process →	+0.206	+1.279	<.001	<.001	3	19
BONE	'de novo' XMP biosynthetic process →	+0.206	+1.279	<.001	<.001	3	19
LIVER	rRNA 5'-end processing →	+0.182	+0.978	<.001	<.001	3	19
OESOPHAGUS	IMP biosynthetic process →	+0.203	+1.228	<.001	<.001	3	19
OESOPHAGUS	'de novo' IMP biosynthetic process →	+0.240	+1.241	<.001	.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,892 associations by consensus.

XMP metabolic process by DHX33 expression — BONE

Explore this box plot interactively →