DHX29

Across TCGA patient cohorts, DHX29 mutation is significantly associated with the RNA expression of many other genes, with 4,393 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DHX29-associated genes across cancer lineages are HBAP1, MIR1225, and FANCE. Each is linked with DHX29 in more than 3 cancer types. Because this analysis shows association rather than direction, both DHX29-to-partner and partner-to-DHX29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HBAP1 grouped by DHX29-low versus DHX29-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX29→partner) and Y-score (partner→DHX29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	HBAP1 →	+0.135	+5.039	<.001	.009	3	4
LUAD	MIR1225 →	+0.102	+4.748	<.001	.003	3	3
COAD	FANCE →	+0.434	+3.403	.006	.004	3	3
COAD	CCNB1 →	+0.716	+3.362	.001	.005	3	3
UCEC	HAUS2 →	+0.608	+1.830	<.001	<.001	3	3
BLCA	RNU1-19P →	+0.283	+4.715	.008	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,393 associations by consensus.

HBAP1 by DHX29 expression — LGG

Explore this box plot interactively →