DHX29

Across TCGA patient cohorts, DHX29 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DHX29-associated genes across cancer lineages are PDCD4, Caspase-8, and 14-3-3_beta. Each is linked with DHX29 in more than 2 cancer types. Because this analysis shows association rather than direction, both DHX29-to-partner and partner-to-DHX29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by DHX29-low versus DHX29-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX29→partner) and Y-score (partner→DHX29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.326	-1.584	.021	.032	3	3
UCEC	Caspase-8 →	-0.242	-2.780	.001	<.001	3	2
UCEC	14-3-3_beta →	-0.100	-1.973	.001	.008	3	2
UCEC	eIF4E →	+0.212	+3.713	<.001	<.001	3	2
UCEC	A-Raf_pS299 →	-0.117	-1.765	.001	.013	3	2
UCEC	p70-S6K →	+0.125	+1.557	.032	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

PDCD4 by DHX29 expression — UCEC

Explore this box plot interactively →