DHX29

Across TCGA cell cohorts, DHX29 mutation is significantly associated with the RNA expression of many other genes, with 752 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DHX29-associated genes across cancer lineages are FANCD2OS, POLR1C, and ZNF280B. Each is linked with DHX29 in more than 1 cancer types. Because this analysis shows association rather than direction, both DHX29-to-partner and partner-to-DHX29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FANCD2OS grouped by DHX29-low versus DHX29-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX29→partner) and Y-score (partner→DHX29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	FANCD2OS →	+0.139	+3.432	.005	.006	3	2
LARGE_INTESTINE	POLR1C →	+0.421	+3.628	.003	<.001	3	2
LARGE_INTESTINE	ZNF280B →	+0.666	+3.628	<.001	<.001	3	2
KIDNEY	LY6H →	+0.023	+5.000	<.001	.005	3	1
KIDNEY	AGBL1 →	+0.210	+5.000	<.001	.005	3	1
URINARY_TRACT	HTN1 →	+0.157	+4.044	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 752 associations by consensus.

FANCD2OS by DHX29 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →