Across TCGA patient cohorts, DHX16 mutation is significantly associated with the total protein of many other genes, with 61 significant associations in total. COAD shows the largest number of these associations.

The most reproducible DHX16-associated genes across cancer lineages are Caspase-7-cleavedD198, PKC-a_pS657, and PKC-a. Each is linked with DHX16 in more than 2 cancer types. Because this analysis shows association rather than direction, both DHX16-to-partner and partner-to-DHX16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX16→partner) and Y-score (partner→DHX16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+1.281	+2.476	<.001	.009	3	3
COAD	PKC-a_pS657 →	-0.411	-2.700	<.001	.005	3	3
COAD	PKC-a →	-0.447	-2.584	<.001	.010	3	3
COAD	EGFR_pY1068 →	-0.398	-3.321	.001	.009	3	2
COAD	GAPDH →	+0.576	+2.123	.003	.010	3	2
UCEC	MSH2 →	-0.312	-1.739	<.001	.012	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 61 associations by consensus.

Exploration

DHX16 survival (RNA) · tumor vs normal (RNA) · all DHX16 data types