Across TCGA cell cohorts, DHX16 mutation is significantly associated with the RNA expression of many other genes, with 85 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DHX16-associated genes across cancer lineages are GPR101, TDRD15, and LCE1A. Each is linked with DHX16 in more than 1 cancer types. Because this analysis shows association rather than direction, both DHX16-to-partner and partner-to-DHX16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX16→partner) and Y-score (partner→DHX16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GPR101 →	+0.074	+2.644	<.001	.008	3	2
OESOPHAGUS	TDRD15 →	+0.006	+4.906	<.001	.006	3	1
LUNG_NSCLC_LUSC	LCE1A →	+0.126	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	SPO11 →	+0.033	+4.643	<.001	.008	3	1
LUNG_SCLC	CCL23 →	+0.123	+5.029	<.001	.006	3	1
BLOOD_Leukemia	GALNT16 →	+0.168	+3.449	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 85 associations by consensus.

Exploration

DHX16 survival (RNA) · tumor vs normal (RNA) · all DHX16 data types