DHTKD1

Across TCGA patient cohorts, DHTKD1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,121 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DHTKD1-associated genes across cancer lineages are VGLL3, PMP22, and ELK3. Each is linked with DHTKD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DHTKD1-to-partner and partner-to-DHTKD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHTKD1 versus VGLL3 in OV, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHTKD1→partner) and Y-score (partner→DHTKD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	VGLL3 →	-0.917	-0.415	<.001	<.001	3	7
OV	PMP22 →	-0.836	-0.509	<.001	<.001	3	6
BRCA	ELK3 →	-0.695	-0.614	<.001	<.001	3	6
OV	DCN →	-1.669	-0.620	<.001	<.001	3	6
OV	TGFB3 →	-1.174	-0.444	<.001	<.001	3	6
BRCA	F13A1 →	-1.836	-0.687	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,121 associations by consensus.

DHTKD1 vs VGLL3 — OV

Explore this scatter interactively →