DHTKD1

Across TCGA cell cohorts, DHTKD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,307 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DHTKD1-associated GO terms across cancer lineages are DNA strand elongation, G2/M transition of mitotic cell cycle, and Positive regulation of double-strand break repair. Each is linked with DHTKD1 in more than 10 cancer types. Because this analysis shows association rather than direction, both DHTKD1-to-partner and partner-to-DHTKD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation grouped by DHTKD1-low versus DHTKD1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHTKD1→partner) and Y-score (partner→DHTKD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA strand elongation →	+0.129	+0.826	<.001	.003	3	11
BONE	G2/M transition of mitotic cell cycle →	+0.158	+1.154	<.001	.001	3	11
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.075	+0.879	<.001	<.001	3	10
BONE	Zymogen activation →	-0.204	-0.944	<.001	<.001	3	10
SOFT_TISSUE	Interstrand cross-link repair →	+0.073	+0.992	.002	<.001	2	11
SOFT_TISSUE	Defense response to bacterium →	-0.081	-0.633	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,307 associations by consensus.

DNA strand elongation by DHTKD1 expression — SOFT_TISSUE

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