DHRSX

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DHRSX protein abundance is significantly associated with the RNA expression of many other genes, with 5,460 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DHRSX-associated genes across cancer lineages are E4F1, PGP, and MYO19. Each is linked with DHRSX in more than 2 cancer types. Because this analysis shows association rather than direction, both DHRSX-to-partner and partner-to-DHRSX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHRSX versus E4F1 in LSCC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRSX→partner) and Y-score (partner→DHRSX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCE4F1 →-0.255-0.230<.001.00733
LUADPGP →-0.348-0.288<.001.00333
LSCCMYO19 →-0.404-0.303<.001<.00133
LSCCKIF22 →-0.686-0.392.001.00133
LUADCELSR3 →-0.991-0.426<.001<.00133
LSCCCAD →-0.649-0.384<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,460 associations by consensus.

DHRSX vs E4F1 — LSCC

Per-sample scatter of DHRSX vs E4F1 in LSCC (Pearson r = -0.33).

Explore this scatter interactively →

Exploration