Across TCGA patient cohorts, DHRS7C protein abundance is significantly associated with the RNA expression of many other genes, with 1,144 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DHRS7C-associated genes across cancer lineages are CTSG, ASB2, and SLC8A3. Each is linked with DHRS7C in more than 1 cancer types. Because this analysis shows association rather than direction, both DHRS7C-to-partner and partner-to-DHRS7C results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS7C→partner) and Y-score (partner→DHRS7C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CTSG →	+1.455	+0.855	.001	.006	3	1
HNSC	ASB2 →	+1.035	+1.032	<.001	<.001	3	1
HNSC	SLC8A3 →	+0.912	+1.441	<.001	<.001	3	1
HNSC	TCL1A →	+0.866	+0.729	.005	.004	3	1
HNSC	EEF1A2 →	+1.715	+0.920	<.001	<.001	3	1
HNSC	MYLK2 →	+1.254	+1.050	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,144 associations by consensus.

Exploration

DHRS7C survival (RNA) · tumor vs normal (RNA) · all DHRS7C data types