Across TCGA patient cohorts, DHRS7C mutation is significantly associated with the RNA expression of many other genes, with 3,128 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DHRS7C-associated genes across cancer lineages are CENPUP1, BANP, and CHCHD1. Each is linked with DHRS7C in more than 2 cancer types. Because this analysis shows association rather than direction, both DHRS7C-to-partner and partner-to-DHRS7C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS7C→partner) and Y-score (partner→DHRS7C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPUP1 →	+0.165	+2.001	<.001	.004	3	3
UCEC	BANP →	+0.435	+2.269	<.001	.001	3	3
UCEC	CHCHD1 →	+0.322	+1.847	.008	.009	3	3
HNSC	MRPL32P1 →	+0.225	+5.608	<.001	.002	3	3
BRCA	MIR6779 →	+0.770	+4.580	<.001	.004	3	2
BRCA	RNU6-1236P →	+0.186	+7.473	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,128 associations by consensus.

Exploration

DHRS7C survival (RNA) · tumor vs normal (RNA) · all DHRS7C data types