DHRS7C

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DHRS7C mutation is significantly associated with the total protein of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DHRS7C-associated genes across cancer lineages are ASNS, FoxM1, and INPP4B. Each is linked with DHRS7C in more than 3 cancer types. Because this analysis shows association rather than direction, both DHRS7C-to-partner and partner-to-DHRS7C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS7C→partner) and Y-score (partner→DHRS7C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECASNS →+0.366+1.874.008.04934
UCECFoxM1 →+0.270+2.087.006.00532
UCECINPP4B →-0.317-2.074.010.00532
UCECMEK1 →+0.469+3.000<.001<.00132
UCEC4E-BP1 →+0.410+2.584<.001.01032
SKCMPKC-a →-0.401-3.000.027.03532
Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

Exploration