Across TCGA cell cohorts, DHRS7C mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DHRS7C-associated genes across cancer lineages are TNP1, FGF3, and MYBPC3. Each is linked with DHRS7C in more than 1 cancer types. Because this analysis shows association rather than direction, both DHRS7C-to-partner and partner-to-DHRS7C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS7C→partner) and Y-score (partner→DHRS7C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TNP1 →	+0.172	+5.415	<.001	.004	3	1
CNS	FGF3 →	+0.043	+4.981	<.001	.008	3	1
SKIN	MYBPC3 →	+0.008	+3.688	.002	.002	3	1
SKIN	PSKH2 →	+0.027	+3.632	<.001	.003	3	1
SKIN	HMHB1 →	+0.038	+4.022	<.001	.006	3	1
SKIN	GP2 →	+0.164	+3.453	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

DHRS7C survival (RNA) · tumor vs normal (RNA) · all DHRS7C data types