Across TCGA patient cohorts, DHRS4L2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,983 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DHRS4L2-associated proteins across cancer lineages are DHRS4, FKBP3, and MTHFD1. Each is linked with DHRS4L2 in more than 9 cancer types. Because this analysis shows association rather than direction, both DHRS4L2-to-partner and partner-to-DHRS4L2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS4L2→partner) and Y-score (partner→DHRS4L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	DHRS4 →	+0.609	+0.424	<.001	<.001	3	10
OV	FKBP3 →	+0.440	+0.564	<.001	<.001	2	8
OV	MTHFD1 →	+0.342	+0.623	.003	.001	3	7
GBM	SSRP1 →	+0.446	+0.286	.002	.001	3	7
COAD	PRMT5 →	+0.369	+0.715	<.001	<.001	3	6
HNSC	UBR7 →	+0.289	+0.438	<.001	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,983 associations by consensus.

Exploration

DHRS4L2 survival (RNA) · tumor vs normal (RNA) · all DHRS4L2 data types