Across TCGA patient cohorts, DHRS4L2 mutation is significantly associated with the RNA expression of many other genes, with 185 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DHRS4L2-associated genes across cancer lineages are OR8K4P, MIR1263, and CENPU. Each is linked with DHRS4L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DHRS4L2-to-partner and partner-to-DHRS4L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS4L2→partner) and Y-score (partner→DHRS4L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR8K4P →	+0.074	+7.640	<.001	.009	3	2
COAD	MIR1263 →	+1.494	+7.741	<.001	.009	3	2
UCEC	CENPU →	+0.778	+3.491	.008	.002	3	1
UCEC	SLC25A28 →	+0.452	+3.201	.001	.009	3	1
UCEC	SIGLEC11 →	+0.920	+3.513	<.001	.002	3	1
UCEC	CHAF1A →	+0.645	+3.480	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 185 associations by consensus.

Exploration

DHRS4L2 survival (RNA) · tumor vs normal (RNA) · all DHRS4L2 data types