Across TCGA cell cohorts, DHRS4L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,058 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DHRS4L2-associated GO terms across cancer lineages are Retinal metabolic process, Aldehyde metabolic process, and Protein linear polyubiquitination. Each is linked with DHRS4L2 in more than 11 cancer types. Because this analysis shows association rather than direction, both DHRS4L2-to-partner and partner-to-DHRS4L2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS4L2→partner) and Y-score (partner→DHRS4L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Retinal metabolic process →	+0.188	+0.652	<.001	.007	3	12
URINARY_TRACT	Aldehyde metabolic process →	+0.108	+0.943	.001	.003	3	10
URINARY_TRACT	Protein linear polyubiquitination →	+0.148	+1.022	<.001	.003	3	8
OVARY	ERBB3 signaling pathway →	+0.160	+0.709	.008	.009	3	7
OVARY	ERBB2-ERBB3 signaling pathway →	+0.160	+0.709	.008	.009	3	7
BREAST	Positive regulation of protein K63-linked ubiquitination →	-0.137	-0.904	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,058 associations by consensus.

Exploration

DHRS4L2 survival (RNA) · tumor vs normal (RNA) · all DHRS4L2 data types