DHRS3

Across TCGA patient cohorts, DHRS3 protein abundance is significantly associated with the RNA expression of many other genes, with 15,013 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DHRS3-associated genes across cancer lineages are RDH10, RDH10-AS1, and RNU6ATAC18P. Each is linked with DHRS3 in more than 8 cancer types. Because this analysis shows association rather than direction, both DHRS3-to-partner and partner-to-DHRS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHRS3 versus RDH10 in LSCC, with a Pearson correlation of 0.77.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS3→partner) and Y-score (partner→DHRS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RDH10 →	+1.563	+0.905	<.001	<.001	3	9
LSCC	RDH10-AS1 →	+1.132	+0.802	<.001	<.001	3	8
GBM	RNU6ATAC18P →	+1.221	+0.800	<.001	<.001	2	7
UCEC	MIR6730 →	+1.307	+0.517	.003	.005	3	6
LUAD	PPP1R18 →	-0.489	-0.409	<.001	<.001	3	5
GBM	C18orf54 →	-0.692	-0.635	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,013 associations by consensus.

DHRS3 vs RDH10 — LSCC

Explore this scatter interactively →