DHRS12

Across TCGA patient cohorts, DHRS12 mutation is significantly associated with the immune_cell of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DHRS12-associated genes across cancer lineages are CLP, Endothelial cells, and lymphatic Endothelial cells. Each is linked with DHRS12 in more than 1 cancer types. Because this analysis shows association rather than direction, both DHRS12-to-partner and partner-to-DHRS12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLP grouped by DHRS12-low versus DHRS12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS12→partner) and Y-score (partner→DHRS12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CLP →	-0.050	-3.169	.045	.019	3	1
UCEC	Endothelial cells →	-0.041	-3.300	.006	.010	3	1
UCEC	lymphatic Endothelial cells →	-0.023	-1.853	.015	.017	3	1
UCEC	Mast cells →	+0.013	+1.528	.044	.035	3	1
UCEC	Mesangial cells →	-0.036	-2.404	.019	.003	3	1
UCEC	mv Endothelial cells →	-0.025	-2.269	.008	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

CLP by DHRS12 expression — UCEC

Explore this box plot interactively →