DHRS12

Across TCGA cell cohorts, DHRS12 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,016 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DHRS12-associated GO terms across cancer lineages are Lysosome organization, Lytic vacuole organization, and Cilium or flagellum-dependent cell motility. Each is linked with DHRS12 in more than 9 cancer types. Because this analysis shows association rather than direction, both DHRS12-to-partner and partner-to-DHRS12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lysosome organization grouped by DHRS12-low versus DHRS12-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS12→partner) and Y-score (partner→DHRS12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Lysosome organization →	+0.054	+0.739	<.001	.001	3	10
BREAST	Lytic vacuole organization →	+0.054	+0.739	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.081	-0.762	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, vesicle recycling within Golgi →	+0.113	+1.052	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.133	-1.166	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.081	-0.762	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,016 associations by consensus.

Lysosome organization by DHRS12 expression — BREAST

Explore this box plot interactively →