DHH

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DHH RNA expression is significantly associated with the protein abundance of many other proteins, with 13,945 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DHH-associated proteins across cancer lineages are SGCD, ITGA7, and KANK3. Each is linked with DHH in more than 6 cancer types. Because this analysis shows association rather than direction, both DHH-to-partner and partner-to-DHH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHH versus SGCD in HNSC, with a Pearson correlation of 0.20.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DHH→partner) and Y-score (partner→DHH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCSGCD →+0.745+0.354<.001.00637
BRCAITGA7 →+0.560+0.164<.001<.00137
BRCAKANK3 →+0.421+0.186<.001<.00137
COADCACNA2D1 →+0.587+0.175<.001<.00137
OVTAGLN →+0.928+0.159<.001<.00136
BRCATNS2 →+0.370+0.229<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,945 associations by consensus.

DHH vs SGCD — HNSC

Per-sample scatter of DHH vs SGCD in HNSC (Pearson r = 0.20).

Explore this scatter interactively →

Exploration