DHH

Across TCGA patient cohorts, DHH protein abundance is significantly associated with the RNA expression of many other genes, with 677 significant associations in total. OV shows the largest number of these associations.

The most reproducible DHH-associated genes across cancer lineages are PPIL2, SLC25A1, and HIRA. Each is linked with DHH in more than 1 cancer types. Because this analysis shows association rather than direction, both DHH-to-partner and partner-to-DHH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHH versus PPIL2 in OV, with a Pearson correlation of -0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHH→partner) and Y-score (partner→DHH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PPIL2 →	-0.940	-1.156	.001	<.001	3	1
OV	SLC25A1 →	-1.087	-1.051	<.001	<.001	3	1
OV	HIRA →	-0.658	-1.113	<.001	.001	3	1
OV	GCAT →	-0.899	-1.179	<.001	<.001	3	1
OV	RASL10A →	-0.447	-1.147	.004	.005	3	1
OV	ASCC2 →	-0.931	-0.871	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 677 associations by consensus.

DHH vs PPIL2 — OV

Explore this scatter interactively →