DHH

Across TCGA cell cohorts, DHH RNA expression is significantly associated with the go_rna of many other GO terms, with 1,860 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DHH-associated GO terms across cancer lineages are Process utilizing autophagic mechanism, Autophagy, and Macroautophagy. Each is linked with DHH in more than 6 cancer types. Because this analysis shows association rather than direction, both DHH-to-partner and partner-to-DHH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Process utilizing autophagic mechanism grouped by DHH-low versus DHH-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHH→partner) and Y-score (partner→DHH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Process utilizing autophagic mechanism →	+0.078	+0.054	<.001	.008	3	7
LUNG_NSCLC_LUSC	Autophagy →	+0.078	+0.054	<.001	.008	3	7
LUNG_NSCLC_LUSC	Macroautophagy →	+0.080	+0.062	<.001	.001	3	7
OESOPHAGUS	Negative regulation of macroautophagy →	+0.086	+0.160	<.001	.002	3	7
OESOPHAGUS	Regulation of focal adhesion assembly →	+0.094	+0.135	.003	.008	3	7
OESOPHAGUS	Regulation of cell-substrate junction assembly →	+0.094	+0.135	.003	.008	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,860 associations by consensus.

Process utilizing autophagic mechanism by DHH expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →