DHDH

Across TCGA patient cohorts, DHDH RNA expression is significantly associated with the protein abundance of many other proteins, with 10,963 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible DHDH-associated proteins across cancer lineages are GINS4, ZWILCH, and ESF1_S153. Each is linked with DHDH in more than 4 cancer types. Because this analysis shows association rather than direction, both DHDH-to-partner and partner-to-DHDH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHDH versus GINS4 in UCEC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DHDH→partner) and Y-score (partner→DHDH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GINS4 →	+0.806	+1.136	<.001	<.001	3	5
UCEC	ZWILCH →	+0.349	+0.598	.004	.005	3	4
UCEC	ESF1_S153 →	+0.758	+0.737	.002	.001	3	4
UCEC	GINS3 →	+0.561	+0.819	<.001	<.001	3	4
BRCA	SRGAP1 →	-0.439	-0.887	<.001	<.001	3	4
OV	ANP32E →	+0.583	+0.798	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,963 associations by consensus.

DHDH vs GINS4 — UCEC

Explore this scatter interactively →