DGUOK

Across TCGA pan-cancer cohorts, DGUOK mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated DGUOK data layer compared with 26 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher DGUOK mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DGUOK expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and CCRCC are the cancer types where DGUOK mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.894	.030	30	view →
PDAC	DFS	Median	All	0.458	0.257	.010	18	view →
CCRCC	DFS	Quartile	All	0.854	1.000	.006	15	view →
HNSC	DFS	Median	III,IV	0.886	0.734	.048	1	view →
LUAD	DFS	Tertile	All	0.883	0.545	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DGUOK–COAD (DFS)

Open the COAD breakdown →