DGUOK

Across TCGA patient cohorts, DGUOK protein abundance is significantly associated with the RNA expression of many other genes, with 8,534 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DGUOK-associated genes across cancer lineages are GBP1, STIP1, and CEBPZOS. Each is linked with DGUOK in more than 4 cancer types. Because this analysis shows association rather than direction, both DGUOK-to-partner and partner-to-DGUOK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGUOK versus GBP1 in BRCA, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DGUOK→partner) and Y-score (partner→DGUOK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GBP1 →	-1.094	-0.347	.001	.001	3	5
PDAC	STIP1 →	-0.396	-0.354	<.001	<.001	3	4
LSCC	CEBPZOS →	+0.493	+0.261	.004	.004	3	4
UCEC	CYTOR →	-0.792	-0.424	<.001	<.001	3	4
GBM	LINC01943 →	-0.715	-0.268	.002	<.001	2	5
GBM	RPS4XP16 →	+0.612	+0.255	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,534 associations by consensus.

DGUOK vs GBP1 — BRCA

Explore this scatter interactively →