DGUOK

Across TCGA cell cohorts, DGUOK RNA expression is significantly associated with the go_rna of many other GO terms, with 2,830 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DGUOK-associated GO terms across cancer lineages are Tumor necrosis factor-mediated signaling pathway, Regulation of DNA damage checkpoint, and NADPH regeneration. Each is linked with DGUOK in more than 9 cancer types. Because this analysis shows association rather than direction, both DGUOK-to-partner and partner-to-DGUOK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tumor necrosis factor-mediated signaling pathway grouped by DGUOK-low versus DGUOK-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DGUOK→partner) and Y-score (partner→DGUOK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Tumor necrosis factor-mediated signaling pathway →	-0.050	-0.402	.001	.003	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA damage checkpoint →	+0.109	+0.790	<.001	.001	3	9
UPPER_AERODIGESTIVE_TRACT	NADPH regeneration →	+0.095	+0.727	.001	<.001	3	9
OVARY	Pentose-phosphate shunt, non-oxidative branch →	+0.097	+0.449	.001	.003	2	10
BONE	Negative regulation of protein folding →	+0.077	+0.530	.001	.003	3	8
LUNG_SCLC	Regulation of nucleotide catabolic process →	-0.076	-0.469	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,830 associations by consensus.

Tumor necrosis factor-mediated signaling pathway by DGUOK expression — PANCREAS

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