DGKZP1

Across TCGA pan-cancer cohorts, DGKZP1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of DGKZP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where DGKZP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DGKZP1 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

KIRC, COAD, and HNSC are the cancer types where DGKZP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DGKZP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.658	<.001	12	view →
COAD	All	III,IV	+1.084	<.001	11	view →
HNSC	Male	All	+0.449	<.001	9	view →
LIHC	Female	II,III,IV	+0.272	<.001	9	view →
LUSC	Male	All	+0.596	<.001	7	view →
STAD	All	II,III,IV	+0.582	.001	6	view →
BLCA	Male	All	+0.302	.006	6	view →
THCA	Female	III,IV	+0.292	<.001	6	view →
LUAD	All	All	+0.251	<.001	6	view →
CHOL	All	All	+0.508	<.001	3	view →
KIRP	Female	II,III,IV	−0.301	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

DGKZP1–KIRC

Open the KIRC breakdown →