DGKZ

Across TCGA patient cohorts, DGKZ RNA expression is significantly associated with the protein abundance of many other proteins, with 8,570 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DGKZ-associated proteins across cancer lineages are OXR1_S16, SH2D4A, and LGALS9. Each is linked with DGKZ in more than 3 cancer types. Because this analysis shows association rather than direction, both DGKZ-to-partner and partner-to-DGKZ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGKZ versus OXR1_S16 in LUAD, with a Pearson correlation of -0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKZ→partner) and Y-score (partner→DGKZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	OXR1_S16 →	-0.653	-0.288	.009	<.001	3	3
BRCA	SH2D4A →	-0.521	-0.679	<.001	<.001	3	3
HNSC	LGALS9 →	+0.495	+0.383	.004	.004	2	4
LUAD	UBAP2L_S609 →	+0.482	+0.284	.002	.007	3	3
HNSC	PFDN5 →	+0.161	+0.309	.001	.002	3	3
BRCA	CDC123 →	+0.315	+0.567	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,570 associations by consensus.

DGKZ vs OXR1_S16 — LUAD

Explore this scatter interactively →