DGKH

Across TCGA patient cohorts, DGKH RNA expression is significantly associated with the protein abundance of many other proteins, with 16,733 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DGKH-associated proteins across cancer lineages are KPNA3, MAN2A1, and ZMYM2. Each is linked with DGKH in more than 4 cancer types. Because this analysis shows association rather than direction, both DGKH-to-partner and partner-to-DGKH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGKH versus KPNA3 in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKH→partner) and Y-score (partner→DGKH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KPNA3 →	+0.296	+0.718	<.001	<.001	3	5
GBM	MAN2A1 →	-0.540	-0.438	<.001	.006	3	5
GBM	ZMYM2 →	+0.414	+0.497	<.001	.001	3	5
CCRCC	VCL →	+0.400	+0.524	<.001	<.001	3	4
CCRCC	ZEB1 →	+0.378	+0.601	.002	.003	3	4
BRCA	MYLK →	+0.558	+0.928	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,733 associations by consensus.

DGKH vs KPNA3 — BRCA

Explore this scatter interactively →