DGKH

Across TCGA patient cohorts, DGKH protein abundance is significantly associated with the RNA expression of many other genes, with 10,823 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DGKH-associated genes across cancer lineages are MAPK6P3, GTF2F2, and CHCHD2P11. Each is linked with DGKH in more than 5 cancer types. Because this analysis shows association rather than direction, both DGKH-to-partner and partner-to-DGKH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGKH versus MAPK6P3 in LSCC, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKH→partner) and Y-score (partner→DGKH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MAPK6P3 →	+0.914	+0.397	<.001	<.001	3	6
HNSC	GTF2F2 →	+0.655	+0.274	<.001	.002	3	5
UCEC	CHCHD2P11 →	+0.893	+0.410	.008	.001	3	5
LSCC	FEZ1 →	+0.502	+0.212	<.001	.002	3	4
BRCA	PFKP →	+1.252	+0.356	.001	<.001	3	4
LUAD	RASAL2 →	+0.395	+0.187	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,823 associations by consensus.

DGKH vs MAPK6P3 — LSCC

Explore this scatter interactively →