DGKH

Across TCGA cell cohorts, DGKH RNA expression is significantly associated with the go_rna of many other GO terms, with 4,022 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DGKH-associated GO terms across cancer lineages are Microtubule nucleation, Lipid phosphorylation, and Late viral transcription. Each is linked with DGKH in more than 11 cancer types. Because this analysis shows association rather than direction, both DGKH-to-partner and partner-to-DGKH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule nucleation grouped by DGKH-low versus DGKH-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKH→partner) and Y-score (partner→DGKH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Microtubule nucleation →	+0.086	+0.981	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Lipid phosphorylation →	+0.118	+0.867	<.001	.001	3	11
BLOOD_Leukemia	Late viral transcription →	+0.100	+1.033	<.001	<.001	3	11
SOFT_TISSUE	Diacylglycerol metabolic process →	+0.085	+0.869	<.001	<.001	3	10
PANCREAS	Protein localization to cytoskeleton →	+0.064	+0.740	.002	<.001	3	10
CNS	Microtubule polymerization →	+0.089	+0.518	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,022 associations by consensus.

Microtubule nucleation by DGKH expression — BREAST

Explore this box plot interactively →