DGKE

Across TCGA patient cohorts, DGKE protein abundance is significantly associated with the RNA expression of many other genes, with 7,514 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DGKE-associated genes across cancer lineages are FNDC3B, GYS1, and COL6A2. Each is linked with DGKE in more than 3 cancer types. Because this analysis shows association rather than direction, both DGKE-to-partner and partner-to-DGKE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGKE versus FNDC3B in OV, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKE→partner) and Y-score (partner→DGKE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FNDC3B →	-1.089	-0.700	.001	.001	3	4
OV	GYS1 →	-0.943	-0.513	<.001	.003	3	3
GBM	COL6A2 →	-1.745	-0.771	<.001	<.001	3	3
OV	LPP →	-0.849	-0.476	.001	.003	3	3
OV	COL1A2 →	-1.885	-0.578	<.001	.001	3	3
PDAC	VCL →	-0.696	-0.877	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,514 associations by consensus.

DGKE vs FNDC3B — OV

Explore this scatter interactively →