DGCR6L

Across TCGA patient cohorts, DGCR6L mutation is significantly associated with the RNA expression of many other genes, with 66 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DGCR6L-associated genes across cancer lineages are RNU5E-9P, H1-1, and LINC01718. Each is linked with DGCR6L in more than 1 cancer types. Because this analysis shows association rather than direction, both DGCR6L-to-partner and partner-to-DGCR6L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU5E-9P grouped by DGCR6L-low versus DGCR6L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DGCR6L→partner) and Y-score (partner→DGCR6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU5E-9P →	+0.313	+4.662	<.001	.003	3	2
COAD	H1-1 →	+1.116	+5.283	<.001	.006	3	1
BLCA	LINC01718 →	+0.104	+7.640	<.001	.009	3	1
BLCA	USP9YP2 →	+0.039	+7.640	<.001	.009	3	1
SKCM	MIR651 →	+0.268	+7.816	<.001	.008	3	1
UCEC	ODF4 →	+0.206	+2.803	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 66 associations by consensus.

RNU5E-9P by DGCR6L expression — UCEC

Explore this box plot interactively →