DGCR6L

Across TCGA cell cohorts, DGCR6L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,495 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DGCR6L-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and Interleukin-34-mediated signaling pathway. Each is linked with DGCR6L in more than 15 cancer types. Because this analysis shows association rather than direction, both DGCR6L-to-partner and partner-to-DGCR6L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by DGCR6L-low versus DGCR6L-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DGCR6L→partner) and Y-score (partner→DGCR6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Symbiont-mediated disruption of host cellular anatomical structure →	+0.177	+1.289	<.001	.001	3	16
OESOPHAGUS	Symbiont-mediated disruption of host anatomical structure →	+0.177	+1.289	<.001	.001	3	16
URINARY_TRACT	Interleukin-34-mediated signaling pathway →	+0.195	+1.237	<.001	<.001	3	14
BREAST	Regulation of macrophage proliferation →	+0.215	+1.205	<.001	<.001	3	10
BREAST	Positive regulation of macrophage proliferation →	+0.176	+0.860	<.001	.001	3	10
OVARY	Regulation of Golgi inheritance →	+0.158	+0.947	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,495 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by DGCR6L expression — OESOPHAGUS

Explore this box plot interactively →