DGCR6L

Across TCGA cell cohorts, DGCR6L mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DGCR6L-associated genes across cancer lineages are HHLA1 and MAGEB18. Each is linked with DGCR6L in more than 1 cancer types. Because this analysis shows association rather than direction, both DGCR6L-to-partner and partner-to-DGCR6L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HHLA1 grouped by DGCR6L-low versus DGCR6L-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DGCR6L→partner) and Y-score (partner→DGCR6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HHLA1 →	+0.011	+4.551	<.001	.004	3	1
BLOOD_Leukemia	MAGEB18 →	+0.129	+4.152	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

HHLA1 by DGCR6L expression — BLOOD_Leukemia

Explore this box plot interactively →