Across TCGA patient cohorts, DGCR6 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,141 significant associations in total. LGG shows the largest number of these associations.

The most reproducible DGCR6-associated GO terms across cancer lineages are Isopentenyl diphosphate biosynthetic process, Neuronal signal transduction, and Negative regulation of osteoclast development. Each is linked with DGCR6 in more than 16 cancer types. Because this analysis shows association rather than direction, both DGCR6-to-partner and partner-to-DGCR6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DGCR6→partner) and Y-score (partner→DGCR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	Isopentenyl diphosphate biosynthetic process →	+0.066	+0.789	<.001	<.001	3	17
LAML	Neuronal signal transduction →	+0.120	+0.480	<.001	<.001	3	15
ESCA	Negative regulation of osteoclast development →	-0.068	-0.443	<.001	<.001	3	14
PAAD	Positive regulation of platelet activation →	-0.054	-0.348	.001	<.001	3	14
ESCA	Interleukin-5-mediated signaling pathway →	-0.081	-0.621	<.001	<.001	3	14
ACC	Nucleoside bisphosphate catabolic process →	+0.047	+0.812	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,141 associations by consensus.

Exploration

DGCR6 survival (RNA) · tumor vs normal (RNA) · all DGCR6 data types