Across TCGA patient cohorts, DGCR6 protein abundance is significantly associated with the RNA expression of many other genes, with 187 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DGCR6-associated genes across cancer lineages are SLC16A8, NOL3, and SDHAF4. Each is linked with DGCR6 in more than 1 cancer types. Because this analysis shows association rather than direction, both DGCR6-to-partner and partner-to-DGCR6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DGCR6→partner) and Y-score (partner→DGCR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLC16A8 →	+1.222	+0.549	.001	.001	3	1
BRCA	NOL3 →	+1.687	+0.658	.004	.004	3	1
BRCA	SDHAF4 →	+1.111	+0.477	.005	.009	3	1
BRCA	H2AZ1 →	-0.734	-0.549	.004	.002	3	1
BRCA	MOGAT2 →	+1.478	+0.545	<.001	.001	3	1
BRCA	SNRPD1 →	-0.594	-0.597	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 187 associations by consensus.

Exploration

DGCR6 survival (RNA) · tumor vs normal (RNA) · all DGCR6 data types