DGCR11

Across TCGA patient cohorts, DGCR11 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,185 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DGCR11-associated proteins across cancer lineages are TRMT2A, TPMT, and RANBP1. Each is linked with DGCR11 in more than 4 cancer types. Because this analysis shows association rather than direction, both DGCR11-to-partner and partner-to-DGCR11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGCR11 versus TRMT2A in LSCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DGCR11→partner) and Y-score (partner→DGCR11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRMT2A →	+0.352	+0.499	<.001	<.001	3	5
LSCC	TPMT →	+0.255	+0.322	<.001	.001	3	3
LSCC	RANBP1 →	+0.312	+0.310	<.001	<.001	3	3
PDAC	RANGAP1 →	+0.222	+0.269	<.001	.001	3	3
PDAC	COMT →	+0.428	+0.318	<.001	.001	3	3
GBM	CRKL →	+0.224	+0.391	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,185 associations by consensus.

DGCR11 vs TRMT2A — LSCC

Explore this scatter interactively →