DGAT2L6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DGAT2L6 mutation is significantly associated with the RNA expression of many other genes, with 3,613 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DGAT2L6-associated genes across cancer lineages are MIR8070, RNU6-1318P, and NIFKP4. Each is linked with DGAT2L6 in more than 2 cancer types. Because this analysis shows association rather than direction, both DGAT2L6-to-partner and partner-to-DGAT2L6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DGAT2L6→partner) and Y-score (partner→DGAT2L6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR8070 →+0.410+1.565<.001.00833
HNSCRNU6-1318P →+0.333+3.639<.001.00633
COADNIFKP4 →+0.072+3.596.002.00432
LIHCSNORD53 →+0.538+4.207.003.00932
LIHCRN7SL524P →+0.152+4.607<.001.00432
UCECTAF9 →+0.508+3.115<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,613 associations by consensus.

Exploration