Across TCGA patient cohorts, DGAT2L6 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DGAT2L6-associated genes across cancer lineages are GAPDH, p62 Lck ligand, and AMPK_alpha. Each is linked with DGAT2L6 in more than 1 cancer types. Because this analysis shows association rather than direction, both DGAT2L6-to-partner and partner-to-DGAT2L6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DGAT2L6→partner) and Y-score (partner→DGAT2L6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GAPDH →	+0.574	+3.000	.049	.035	3	1
SKCM	p62 Lck ligand →	+0.467	+2.321	.015	.035	3	1
SKCM	AMPK_alpha →	+0.187	+2.321	.007	.035	3	1
SKCM	Smad4 →	+0.137	+2.841	.015	.033	3	1
SKCM	ASNS →	+0.568	+2.321	.008	.035	3	1
UCEC	EGFR_pY1068 →	-0.199	-1.502	.031	.030	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

DGAT2L6 survival (RNA) · tumor vs normal (RNA) · all DGAT2L6 data types