DGAT2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DGAT2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,707 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DGAT2-associated genes across cancer lineages are RASD2, ITPK1, and FERMT1. Each is linked with DGAT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DGAT2-to-partner and partner-to-DGAT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGAT2 versus RASD2 in BRCA, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DGAT2→partner) and Y-score (partner→DGAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCARASD2 →+1.586+0.609.002.00331
BRCAITPK1 →-1.186-0.771.008.00431
BRCAFERMT1 →+1.876+0.952.001<.00131
BRCAVGLL1 →+3.324+0.659.001.00131
BRCAMAGED2 →-2.093-0.960.001<.00131
BRCATNFSF13B →+1.288+1.030.003.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,707 associations by consensus.

DGAT2 vs RASD2 — BRCA

Per-sample scatter of DGAT2 vs RASD2 in BRCA (Pearson r = 0.58).

Explore this scatter interactively →

Exploration