DFFB

Across TCGA patient cohorts, DFFB RNA expression is significantly associated with the protein abundance of many other proteins, with 12,840 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DFFB-associated proteins across cancer lineages are LRRC47, HNRNPR, and RCC2. Each is linked with DFFB in more than 5 cancer types. Because this analysis shows association rather than direction, both DFFB-to-partner and partner-to-DFFB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DFFB versus LRRC47 in OV, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DFFB→partner) and Y-score (partner→DFFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LRRC47 →	+0.437	+0.695	<.001	<.001	3	6
GBM	HNRNPR →	+0.341	+0.408	<.001	<.001	3	6
GBM	RCC2 →	+0.382	+0.297	<.001	<.001	3	5
GBM	RBM22 →	+0.266	+0.381	<.001	<.001	3	5
GBM	MFAP1 →	+0.309	+0.312	<.001	<.001	3	5
GBM	IK →	+0.271	+0.316	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,840 associations by consensus.

DFFB vs LRRC47 — OV

Explore this scatter interactively →