DFFB

Across TCGA patient cohorts, DFFB protein abundance is significantly associated with the RNA expression of many other genes, with 4,225 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible DFFB-associated genes across cancer lineages are DNAJC11, DFFA, and RERE. Each is linked with DFFB in more than 4 cancer types. Because this analysis shows association rather than direction, both DFFB-to-partner and partner-to-DFFB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DFFB versus DNAJC11 in OV, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DFFB→partner) and Y-score (partner→DFFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DNAJC11 →	+0.542	+0.286	<.001	<.001	3	5
OV	DFFA →	+0.684	+0.371	<.001	<.001	3	5
OV	RERE →	+0.964	+0.286	<.001	<.001	3	5
OV	EMC1 →	+0.843	+0.438	<.001	<.001	3	4
OV	PGD →	+0.645	+0.429	<.001	.001	3	4
HNSC	CST6 →	-1.505	-0.192	.001	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,225 associations by consensus.

DFFB vs DNAJC11 — OV

Explore this scatter interactively →